Description

Potassium (3-Chloro-2-(4-Methylpiperidin-1-Yl)Pyridin-4-Yl)Trifluoroborate is a high-value organotrifluoroborate salt, a crucial class of intermediates in modern synthetic chemistry. This compound is specifically engineered for use in advanced cross-coupling reactions, offering superior stability and handling compared to traditional boronic acids. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the efficient construction of complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable and efficient boron-based coupling partner for the synthesis of biaryl and heterobiaryl structures, which are core scaffolds in many active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Serves as a key building block in the research and development of novel drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific, complex heterocyclic motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology Probes: Useful for the synthesis of tagged molecules and probes for studying biological pathways and target engagement.
• Process Chemistry & Scale-Up: Its improved stability makes it suitable for optimizing and scaling up synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	Potassium (3-Chloro-2-(4-Methylpiperidin-1-Yl)Pyridin-4-Yl)Trifluoroborate
CAS No.	1704704-42-6
Molecular Formula	C11H14BClF3KN2
Molecular Weight	328.60 g/mol
Synonyms	Potassium (3-Chloro-2-(4-methylpiperidin-1-yl)pyridin-4-yl)trifluoroborate; 3-Chloro-2-(4-methyl-1-piperidinyl)-4-pyridinyltrifluoroborate potassium salt; Potassium 3-Chloro-2-(4-methylpiperidin-1-yl)pyridin-4-yltrifluoroborate; (3-Chloro-2-(4-methylpiperidin-1-yl)pyridin-4-yl)trifluoroborate Potassium; KF3B-Pyridine Derivative; Organotrifluoroborate Salt; Suzuki Coupling Boron Reagent
EINECS	Contact for details

Quality Control

Every batch of Potassium (3-Chloro-2-(4-Methylpiperidin-1-Yl)Pyridin-4-Yl)Trifluoroborate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent decomposition. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.