Description

(4-(3-(4-((tert-Butyldiphenylsilyl)Oxy)Piperidin-1-Yl)Propoxy)-3-Chlorophenyl)Boronic Acid is a sophisticated, high-value boronic acid derivative designed for advanced synthetic chemistry. This compound matters as a critical building block in modern pharmaceutical research, particularly for constructing complex molecules via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl structures.
• Medicinal Chemistry & SAR Studies: Used in structure-activity relationship (SAR) explorations to optimize the potency and selectivity of lead compounds.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Research: Utilized in the discovery and synthesis of new active ingredients for crop protection products.
• Advanced Materials Synthesis: A potential monomer or intermediate for creating organic electronic materials, polymers, and liquid crystals.

Basic Information

Item	Details
Product Name	(4-(3-(4-((tert-Butyldiphenylsilyl)Oxy)Piperidin-1-Yl)Propoxy)-3-Chlorophenyl)Boronic Acid
CAS No.	1704082-47-2
Molecular Formula	C34H45BClNO4Si
Molecular Weight	606.08 g/mol
Synonyms	4-(3-(4-((tert-Butyldiphenylsilyl)oxy)piperidin-1-yl)propoxy)-3-chlorobenzeneboronic acid; 3-Chloro-4-[3-[4-[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-piperidinyl]propoxy]benzeneboronic acid; (3-Chloro-4-(3-(4-((tert-butyldiphenylsilyl)oxy)piperidin-1-yl)propoxy)phenyl)boronic acid; Boronic acid, B-[3-chloro-4-[[3-[4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-piperidinyl]propoxy]phenyl]-; TBDPS-protected piperidine boronic acid derivative; CAS 1704082-47-2
EINECS	Contact for details

Quality Control

Our (4-(3-(4-((tert-Butyldiphenylsilyl)Oxy)Piperidin-1-Yl)Propoxy)-3-Chlorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with high-purity research standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.