Description

Chloro(2-Methylphenyl)(N,N,N',N'-Tetramethyl-1,2-Ethylenediamine)Nickel(II) is a specialized organonickel complex valued for its role as a versatile catalyst precursor in advanced organic synthesis. This compound is particularly significant for facilitating challenging cross-coupling and C-H activation reactions, enabling the efficient construction of complex molecular architectures. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel synthetic pathways.

Application

• Catalyst Precursor for Cross-Coupling Reactions: Employed in Kumada, Negishi, and related C-C bond-forming reactions to synthesize biaryl and other complex organic structures.
• C-H Activation and Functionalization: Used as a key component in catalytic systems designed for the direct and selective functionalization of inert C-H bonds.
• Polymerization Catalyst: Serves as a catalyst or co-catalyst in the synthesis of specialty polymers and oligomers with controlled architectures.
• Pharmaceutical Intermediate Synthesis: Facilitates the construction of complex, sterically hindered intermediates in active pharmaceutical ingredient (API) development.
• Agrochemical Research & Development: Applied in the synthesis of novel active ingredients and intermediates for crop protection chemicals.
• Materials Science Research: Utilized in the development of novel organometallic frameworks, conductive polymers, and other functional materials.
• Academic & Industrial R&D: A critical reagent for methodological development in synthetic organic and organometallic chemistry laboratories.

Basic Information

Product Name	Chloro(2-Methylphenyl)(N,N,N',N'-Tetramethyl-1,2-Ethylenediamine)Nickel(II)
CAS No.	1702744-45-3
Molecular Formula	C15H26ClN2Ni
Molecular Weight	328.53 g/mol
Synonyms	Chloro(o-tolyl)(TMEDA)nickel(II); Nickel, chloro[2-methylphenyl][(1,1,2,2-tetramethyl-1,2-ethanediyl)bis[nitrilo(2,2-dimethyl-1,1-ethanediyl)]]-; (TMEDA)Ni(o-tolyl)Cl; Chloro(2-methylphenyl)(N,N,N',N'-tetramethylethylenediamine)nickel; Organonickel Catalyst 1702744-45-3; Ni(TMEDA)(o-tolyl)Cl; Chloro(2-methylphenyl)nickel(II) TMEDA complex
EINECS	Contact for details

Quality Control

Our Chloro(2-Methylphenyl)(N,N,N',N'-Tetramethyl-1,2-Ethylenediamine)Nickel(II) is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive catalytic applications. Each lot undergoes rigorous analytical testing, including NMR, elemental analysis, and HPLC, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Green to blue-green crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Nickel (Ni) Content	17.5 - 18.5 %
Solubility	Soluble in common organic solvents (THF, Toluene, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.