Description

2H-Pyran, 2-(3',5'-Difluoro[1,1'-Biphenyl]-4-Yl)-5-Ethyltetrahydro-, (2R,5S)-Rel- is a high-purity, stereochemically defined fluorinated organic intermediate. This compound is of significant value for its role in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate specific biphenyl-pyran motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides or fungicides, where the difluorobiphenyl moiety can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a sophisticated intermediate in the production of fluorinated organic semiconductors and liquid crystal compounds for display technologies.
• Chemical Biology Probe Synthesis: Employed in creating labeled compounds or molecular probes for studying biological pathways and target engagement.
• Catalyst Ligand Development: Potential use as a precursor for chiral ligands in asymmetric catalysis, leveraging its defined stereochemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring this precise chemical scaffold.

Basic Information

Product Name	2H-Pyran, 2-(3',5'-Difluoro[1,1'-Biphenyl]-4-Yl)-5-Ethyltetrahydro-, (2R,5S)-Rel-
CAS No.	1700445-26-6
Molecular Formula	C23H24F2O
Molecular Weight	354.44 g/mol
Synonyms	rel-(2R,5S)-2-(3',5'-Difluoro-[1,1'-biphenyl]-4-yl)-5-ethyltetrahydro-2H-pyran; (2R,5S)-rel-2-(3',5'-Difluorobiphenyl-4-yl)-5-ethyltetrahydro-2H-pyran; 5-Ethyl-2-(3,5-difluoro-4-biphenylyl)tetrahydro-2H-pyran, (2R,5S)-rel-; Biphenyl, 3,5-difluoro-4-[5-ethyltetrahydro-2H-pyran-2-yl]-, (2R,5S)-rel-; CAS 1700445-26-6; Fluorinated Biphenyl-Pyran Intermediate; 2-(3,5-Difluorobiphenyl-4-yl)-5-ethyltetrahydropyran (rel-(2R,5S)-form).
EINECS	Contact for details

Quality Control

Our 2H-Pyran, 2-(3',5'-Difluoro[1,1'-Biphenyl]-4-Yl)-5-Ethyltetrahydro-, (2R,5S)-Rel- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and chiral purity analysis to ensure high chemical and stereochemical purity suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.