Description

1-Amino-3-Methylcyclobutane-1-Carboxylic Acid is a specialized, high-purity cyclobutane-based amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical, conformationally constrained building block for the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for creating peptide mimetics and probing structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs) and investigational drugs.
• Peptidomimetics Research: Used to introduce rigid, cyclobutane scaffolds into peptide backbones to enhance metabolic stability and receptor selectivity.
• Medicinal Chemistry: Serves as a constrained analog of natural amino acids for probing enzyme active sites and optimizing drug candidate properties.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Agrochemical Research: Potential intermediate in the development of new herbicides or plant growth regulators with novel modes of action.
• Academic & Industrial R&D: Fundamental building block for methodological development in organic synthesis and asymmetric catalysis.

Basic Information

Product Name	1-Amino-3-Methylcyclobutane-1-Carboxylic Acid
CAS No.	1694344-90-5
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	3-Methyl-1-aminocyclobutane-1-carboxylic acid; 1-Amino-3-methyl-1-cyclobutanecarboxylic acid; (1-Amino-3-methylcyclobutyl)formic acid; 1-Cyclobutylamino-3-methyl-1-carboxylic acid; AMCBA; 1-Amino-3-methylcyclobutanecarboxylic acid; 3-Methyl-1-aminocyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-Amino-3-Methylcyclobutane-1-Carboxylic Acid adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and chiral analysis to ensure identity, purity, and enantiomeric excess meet exacting customer requirements. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.