Description

Benzamide, 2-Fluoro-n-(1-Methylethyl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl) is a high-purity, advanced pharmaceutical intermediate featuring a boronic ester pinacol group, making it a critical building block for modern synthetic chemistry. This compound is specifically engineered for use in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for creating complex biaryl structures. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, particularly for targeted therapies and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted small-molecule drugs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Synthesis: Enables the efficient formation of carbon-carbon bonds via palladium-catalyzed cross-coupling reactions to construct complex molecular architectures.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Life Science Reagents: Used in the preparation of biochemical probes and diagnostic agents for research and development.

Basic Information

Item	Details
Product Name	Benzamide, 2-Fluoro-n-(1-Methylethyl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)
CAS No.	1689511-55-4
Molecular Formula	C16H23BFNO3
Molecular Weight	307.17 g/mol
Synonyms	2-Fluoro-N-isopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 5-Boronic acid, 2-fluoro-N-(1-methylethyl)benzamide, pinacol ester; N-Isopropyl-2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(propan-2-yl)benzamide; 1689511-55-4; Benzamide, 2-fluoro-N-(1-methylethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-Fluoro-N-isopropyl-5-(pinacolboron)benzamide
EINECS	Contact for details

Quality Control

Our Benzamide, 2-Fluoro-n-(1-Methylethyl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.