Description

Potassium 4-Benzyl-1-(tert-Butoxycarbonyl)Piperazin-2-Yltrifluoroborate is a high-value organotrifluoroborate salt, a crucial class of reagents in modern synthetic chemistry. Its primary value lies in its stability and utility as a coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing complex piperazine-containing scaffolds found in many drug candidates.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air- and moisture-tolerant organoboron reagent for palladium-catalyzed C-C bond formation.
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science Exploration: Potential precursor for creating functionalized organic materials and ligands for catalysis.
• Process Chemistry & Scale-Up: Employed in route development and optimization for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Academic & Contract Research: A valuable reagent for methodology development and library synthesis in academic and CRO laboratory settings.

Basic Information

Product Name	Potassium 4-Benzyl-1-(tert-Butoxycarbonyl)Piperazin-2-Yltrifluoroborate
CAS No.	1684443-08-0
Molecular Formula	C16H23BF3KN2O2
Molecular Weight	370.18 g/mol
Synonyms	Potassium (1-Boc-4-benzylpiperazin-2-yl)trifluoroborate; 1-Boc-4-Benzylpiperazine-2-trifluoroboronic Acid Potassium Salt; (1-Boc-4-Benzyl-2-piperazinyl)trifluoroborate Potassium Salt; Potassium 1-(tert-Butoxycarbonyl)-4-benzylpiperazine-2-trifluoroborate; Potassium 1-Boc-4-benzyl-1,2,3,6-tetrahydropyrazine-2-trifluoroborate; 4-Benzyl-1-Boc-piperazine-2-trifluoroboronic Acid Potassium Salt; Potassium 4-Benzyl-1-Boc-piperazin-2-yltrifluoroborate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including NMR (1H, 13C, 19F, 11B), HPLC, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with full analytical data are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and potentially moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.