Description

Potassium 1-n-Boc-Pyrrolidin-2-Yltrifluoroborate is a high-purity, organoboron reagent designed for advanced synthetic chemistry. This compound is a valuable building block in modern pharmaceutical research and development, enabling efficient and selective carbon-carbon bond formation. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex, nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent in the preparation of pyrrolidine-based active pharmaceutical ingredients (APIs) and drug candidates.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, potassium-trifluoroborate organometallic partner for palladium-catalyzed cross-coupling, offering advantages in handling and reactivity.
• Medicinal Chemistry & Drug Discovery: Used in library synthesis for structure-activity relationship (SAR) studies and lead optimization.
• Peptidomimetic Construction: Facilitates the incorporation of proline-like, constrained pyrrolidine structures into peptide backbones.
• Agrochemical Research: Employed in the synthesis of novel compounds with potential herbicidal or insecticidal activity.
• Material Science: Potential precursor for boron-containing polymers or advanced organic materials.

Basic Information

Product Name	Potassium 1-n-Boc-Pyrrolidin-2-Yltrifluoroborate
CAS No.	1684443-00-2
Molecular Formula	C9H16BF3KNO2
Molecular Weight	265.14 g/mol
Synonyms	Potassium (2S)-1-[(tert-Butoxy)carbonyl]-2-pyrrolidinyltrifluoroborate; Potassium (S)-1-Boc-2-pyrrolidinyltrifluoroborate; (S)-1-Boc-2-pyrrolidineboronic acid potassium trifluoroborate salt; 1-Boc-2-pyrrolidineboronic acid, potassium trifluoroborate; Potassium 1-(tert-Butoxycarbonyl)-2-pyrrolidinyltrifluoroborate; Potassium 1-Boc-2-pyrrolidinyltrifluoroborate; (S)-1-N-Boc-2-pyrrolidineboronic acid potassium trifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium 1-n-Boc-Pyrrolidin-2-Yltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and development use. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.