Description

5-(1H-Imidazol-1-yl)-1,3-benzenedicarboxylic acid is a high-purity, multifunctional organic building block featuring a rigid aromatic dicarboxylic acid core linked to an imidazole heterocycle. This unique molecular architecture makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty polymer sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzyme inhibition where the imidazole moiety acts as a coordinating ligand.
• Metal-Organic Framework (MOF) Synthesis: Serves as a versatile organic linker due to its multiple coordination sites (carboxylic acid groups and imidazole nitrogen), enabling the construction of porous materials for gas storage, separation, and catalysis.
• Ligand in Coordination Chemistry: Used to create complex metal chelates and catalysts for organic transformations and industrial chemical processes.
• Polymer Modification: Incorporated into polymer backbones to impart thermal stability, rigidity, and specific chemical functionality for high-performance engineering plastics.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, or plant growth regulators.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating novel heterocyclic compounds in academic and industrial R&D labs.

Basic Information

Product Name	5-(1H-Imidazol-1-yl)-1,3-benzenedicarboxylic Acid
CAS No.	1643586-52-0
Molecular Formula	C12H8N2O4
Molecular Weight	244.20 g/mol
Synonyms	5-(1H-Imidazol-1-yl)isophthalic Acid; 1,3-Benzenedicarboxylic acid, 5-(1H-imidazol-1-yl)-; 5-Imidazol-1-ylisophthalic Acid; Imidazole-1,5-dicarboxylic Acid Derivative; AI3-72999; BDBM50403279; ZINC000003869756; SCHEMBL15506211
EINECS	Contact for details

Quality Control

Our 5-(1H-Imidazol-1-yl)-1,3-benzenedicarboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.