Description

(3S,4R)-3-Aminotetrahydro-2H-Pyran-4-Ol CAS NO 1638744-86-1 is a high-purity chiral amino alcohol building block of significant interest in advanced organic synthesis. This compound is valued for its rigid pyran ring structure and defined stereochemistry, which are critical for imparting specific biological activity and physical properties in target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its stereochemistry can influence efficacy and environmental profile.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Peptidomimetics and Bioactive Molecules: The amino alcohol functionality makes it a valuable scaffold for constructing peptidomimetics and other biologically active small molecules.
• Material Science Research: Investigated as a monomer or building block for specialty polymers and functional materials with specific chiral properties.

Basic Information

Product Name	(3S,4R)-3-Aminotetrahydro-2H-Pyran-4-Ol
CAS No.	1638744-86-1
Molecular Formula	C5H11NO2
Molecular Weight	117.15 g/mol
Synonyms	(3S,4R)-3-Amino-4-hydroxytetrahydropyran; (3S,4R)-3-Amino-4-hydroxyoxane; 3-Amino-4-hydroxytetrahydropyran (stereospecific); 4-Pyranol, 3-aminohexahydro-, (3S,4R)-; (3S,4R)-3-Aminotetrahydro-2H-pyran-4-ol; cis-3-Amino-4-hydroxytetrahydropyran; Tetrahydro-2H-pyran-4-ol, 3-amino-, (3S,4R)-
EINECS	Contact for details

Quality Control

Our (3S,4R)-3-Aminotetrahydro-2H-Pyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity, and chiral excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.