Description

trans-3-Amino-4-Hydroxy-Tetrahydropyran Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for creating novel drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides with specific stereochemical requirements.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and catalysts.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthetic chemistry.
• Peptidomimetics: Acts as a constrained scaffold or surrogate for amino acids in the design of peptide-like bioactive molecules.

Basic Information

Product Name	trans-3-Amino-4-Hydroxy-Tetrahydropyran Hydrochloride
CAS No.	1630906-89-6
Molecular Formula	C6H14ClNO2
Molecular Weight	167.63 g/mol
Synonyms	(3R,4S)-3-Amino-4-hydroxytetrahydro-2H-pyran hydrochloride; (3R,4S)-3-Amino-4-hydroxytetrahydropyran hydrochloride; trans-3-Amino-4-hydroxytetrahydro-2H-pyran HCl; 3-Amino-4-hydroxytetrahydropyran hydrochloride (trans); 2H-Pyran, 3-amino-4-hydroxy-tetrahydro-, hydrochloride, (3R,4S)-; 3-Amino-4-hydroxytetrahydropyran HCl; Amino-hydroxy-tetrahydropyran hydrochloride; THP-Amino-HCl derivative
EINECS	Contact for details

Quality Control

Our trans-3-Amino-4-Hydroxy-Tetrahydropyran Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed HPLC, NMR, and optical rotation data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.