Description

cis-2H-Pyran-4-Amine, 3-Fluorotetrahydro- Hydrochloride is a high-purity, fluorinated heterocyclic amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized, chiral scaffold that is essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapeutics.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to introduce fluorine atoms and amine functionality into candidate molecules.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, and insecticides that require fluorinated heterocyclic motifs.
• Chemical Biology: Employed as a probe or linker in the development of biochemical tools and diagnostic agents.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development in asymmetric synthesis and fluorine chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals for client-specific projects.

Basic Information

Item	Detail
Product Name	cis-2H-Pyran-4-Amine, 3-Fluorotetrahydro- Hydrochloride
CAS No.	1630906-37-4
Molecular Formula	C5H9FNO.HCl
Molecular Weight	153.59 g/mol
Synonyms	3-Fluorotetrahydro-2H-pyran-4-amine hydrochloride; (3R,4S)-3-Fluorotetrahydro-2H-pyran-4-amine hydrochloride; (3S,4R)-3-Fluorotetrahydro-2H-pyran-4-amine hydrochloride; cis-3-Fluoro-tetrahydro-2H-pyran-4-ylamine hydrochloride; 4-Amino-3-fluorotetrahydropyran hydrochloride; 3-Fluoro-4-aminotetrahydropyran HCl; Fluorinated tetrahydropyranylamine HCl; 1630906-37-4
EINECS	Contact for details

Quality Control

Our cis-2H-Pyran-4-Amine, 3-Fluorotetrahydro- Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.