Description

1-[(R)-2-Hydroxy-1-Phenylethyl]-3-(3,5-Dimethylphenyl)-4,5-Dihydro-1H-Imidazolium Hexafluorophosphate is a chiral imidazolium salt, a sophisticated organic intermediate of significant interest in advanced synthetic chemistry. Its value lies in its role as a high-purity chiral building block or catalyst precursor for the development of pharmaceuticals and specialty chemicals. This compound is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in asymmetric synthesis and process development.

Application

• Asymmetric Catalysis: Serves as a precursor for chiral N-heterocyclic carbene (NHC) ligands or organocatalysts.
• Pharmaceutical Intermediate: Key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for central nervous system or cardiovascular targets.
• Methodology Development: Used in academic and industrial research to develop new stereoselective synthetic transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value organic molecules for agrochemicals or materials science.
• Ligand Synthesis: Building block for creating tailored chiral ligands used in transition metal catalysis.

Basic Information

Item	Details
Product Name	1-[(R)-2-Hydroxy-1-Phenylethyl]-3-(3,5-Dimethylphenyl)-4,5-Dihydro-1H-Imidazolium Hexafluorophosphate
CAS No.	1630817-29-6
Molecular Formula	C19H23F6N2O2P
Molecular Weight	456.36 g/mol
Synonyms	(R)-1-(2-Hydroxy-1-phenylethyl)-3-(3,5-dimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate; 1-[(1R)-2-Hydroxy-1-phenylethyl]-3-(3,5-dimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate; Chiral Imidazolium Hexafluorophosphate Salt; NHC Salt Precursor; (R)-Imidazolinium Hexafluorophosphate Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.