Description

3(2H)-Pyridazinone, 6-(4-Chlorophenyl)-4,5-Dihydro-5-Methyl-, (5R)- is a high-purity, single-enantiomer chiral building block of significant interest in advanced organic synthesis. Its defined stereochemistry and functionalized pyridazinone core make it a critical intermediate for the research and development of novel active pharmaceutical ingredients (APIs). This compound is primarily targeted at pharmaceutical R&D and fine chemical synthesis sectors requiring precise molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Agrochemical Research: Used as a building block for developing novel herbicides or pesticides with specific stereochemical activity.
• Chemical Biology: Serves as a probe or ligand in the study of enzyme inhibition and receptor binding due to its heterocyclic structure.
• Asymmetric Synthesis: Employed in catalytic and stoichiometric asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced organic materials requiring specific optical or electronic properties.

Basic Information

Product Name	3(2H)-Pyridazinone, 6-(4-Chlorophenyl)-4,5-Dihydro-5-Methyl-, (5R)-
CAS No.	1630760-90-5
Molecular Formula	C11H11ClN2O
Molecular Weight	222.67 g/mol
Synonyms	(5R)-6-(4-Chlorophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone; (R)-6-(4-Chlorophenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone; (R)-5-Methyl-6-(p-chlorophenyl)-4,5-dihydro-3(2H)-pyridazinone; 6-(4-Chlorophenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone (R-enantiomer); (R)-enantiomer of CAS 1630760-89-2; Chiral Pyridazinone Derivative; p-Chlorophenyl Dihydropyridazinone
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity, critical for pharmaceutical applications. Quality is verified through advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC assay), enantiomeric excess (ee), and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.