Description

(2R,4R)-2-Methyltetrahydro-2H-Pyran-4-Amine is a chiral amine derivative of tetrahydropyran, serving as a valuable and versatile building block in advanced organic synthesis. This compound is particularly significant for its role in constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications requiring high-purity chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and stereoselective synthesis studies.

Basic Information

Product Name	(2R,4R)-2-Methyltetrahydro-2H-Pyran-4-Amine
CAS No.	1628898-49-6
Molecular Formula	C6H13NO
Molecular Weight	115.17 g/mol
Synonyms	(2R,4R)-2-Methyl-4-aminotetrahydropyran; (2R,4R)-2-Methyltetrahydropyran-4-amine; (2R,4R)-2-Methyl-4-aminotetrahydro-2H-pyran; (2R,4R)-2-Methyl-4-aminotetrahydropyran; (2R,4R)-2-Methyl-4-aminotetrahydro-2H-pyran; (2R,4R)-2-Methyltetrahydro-2H-pyran-4-ylamine; 4-Amino-2-methyltetrahydropyran, (2R,4R)-
EINECS	Contact for details

Quality Control

Our (2R,4R)-2-Methyltetrahydro-2H-Pyran-4-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee consistent quality and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.