Description

4-Arm-Peg-Cho CAS NO 1628735-51-2 is a multi-arm polyethylene glycol (PEG) derivative functionalized with aldehyde (CHO) end groups, serving as a versatile heterobifunctional crosslinker and building block in advanced material synthesis. Its core value lies in its precisely engineered four-arm star architecture, which provides multiple reactive sites for creating highly branched, three-dimensional polymer networks with controlled density and functionality. This product is essential for researchers and manufacturers in the pharmaceutical, biomedical, and specialty polymer industries who require sophisticated PEGylation, hydrogel formation, and surface modification capabilities.

Application

• Bioconjugation and PEGylation: Used to attach therapeutic proteins, peptides, or drug molecules to PEG chains, improving solubility, stability, and circulation time.
• Hydrogel Fabrication: Acts as a key crosslinking agent for creating biocompatible hydrogels for tissue engineering scaffolds, wound dressings, and controlled drug delivery systems.
• Surface Functionalization: Enables the modification of nanoparticles, diagnostic devices, and biosensor surfaces with aldehyde groups for subsequent biomolecule immobilization.
• Dendrimer and Star Polymer Synthesis: Serves as a core molecule for constructing complex, multi-functional dendritic or star-shaped polymers with tailored properties.
• Diagnostic Reagent Development: Utilized in the preparation of labeled antibodies, enzymes, or other detection probes for immunoassays and clinical diagnostics.
• Material Science Research: Employed in R&D for developing novel smart materials, self-healing polymers, and responsive gels due to its reactive aldehyde termini.

Basic Information

Product Name	4-Arm-Peg-Cho
CAS No.	1628735-51-2
Molecular Formula	Contact for details
Molecular Weight	Variable (based on PEG arm length)
Synonyms	4-Arm PEG Aldehyde; Tetra-Arm PEG-CHO; Four-Arm Polyethylene Glycol Aldehyde; Star-PEG-CHO; 4-Arm PEG-Propionaldehyde; Multi-Arm PEG Aldehyde; PEG Tetraaldehyde; Tetrakis-PEG Aldehyde
EINECS	Contact for details

Quality Control

Our 4-Arm-Peg-Cho is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and functional group analysis (aldehyde content), to confirm its specifications. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, containers should be sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain reactivity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Aldehyde Content (Titration)	≥ 90% of theoretical
Molecular Weight (GPC)	As per ordered grade (e.g., 2k, 5k, 10k, 20k Da)
Moisture Content (KF)	≤ 1.0%
Residual Solvent (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.