Description

(1R,4R)-4-(Aminomethyl)-1-Methylcyclohexan-1-Ol CAS NO 1628012-59-8 is a high-purity, stereochemically defined chiral building block featuring both amino and hydroxyl functional groups. This compound is critical for the synthesis of complex molecules where precise spatial orientation is required for biological activity or material properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced, stereoselective pesticides and herbicides where the specific isomer configuration enhances efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity.
• Peptidomimetics and Bio-conjugates: The aminomethyl and hydroxyl groups allow for incorporation into peptide backbones or as a linker for bioconjugation strategies.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating specialized polymers with unique thermal or mechanical properties.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulatory and research laboratories.

Basic Information

Product Name	(1R,4R)-4-(Aminomethyl)-1-Methylcyclohexan-1-Ol
CAS No.	1628012-59-8
Molecular Formula	C9H19NO
Molecular Weight	157.25 g/mol
Synonyms	(1R,4R)-4-(Aminomethyl)-1-methylcyclohexanol; (1R,4R)-1-Methyl-4-(aminomethyl)cyclohexan-1-ol; 4-(Aminomethyl)-1-methylcyclohexanol (1R,4R)-isomer; trans-4-(Aminomethyl)-1-methylcyclohexan-1-ol; Aminomethylmethylcyclohexanol; Chiral Cyclohexanol Derivative
EINECS	Contact for details

Quality Control

Every batch of (1R,4R)-4-(Aminomethyl)-1-Methylcyclohexan-1-Ol is manufactured under strict quality management systems. We employ advanced analytical techniques including chiral HPLC, NMR, and GC/MS to ensure high enantiomeric excess (ee) and chemical purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.