Description

Potassium 2-Thiophenoyltrifluoroborate is an organoboron reagent belonging to the potassium trifluoroborate salt class, valued for its enhanced stability and handling properties compared to boronic acids. This compound serves as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of carbon-carbon bonds in complex molecule synthesis. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel thiophene-containing compounds.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for creating active pharmaceutical ingredients (APIs) and drug candidates containing the thiophene moiety.
• Agrochemical Development: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate thiophene heterocycles.
• Material Science & Organic Electronics: Employed in the synthesis of conjugated polymers and small molecules for applications in organic light-emitting diodes (OLEDs) and semiconductors.
• Catalytic Cross-Coupling Reactions: Specifically designed as a stable, air-tolerant reagent for robust Suzuki-Miyaura cross-coupling with various aryl and heteroaryl halides.
• Chemical Research & Development: Serves as a versatile synthon in academic and industrial R&D for exploring new chemical spaces and reaction methodologies.
• Ligand and Catalyst Preparation: Used in the synthesis of specialized ligands and organometallic catalysts.

Basic Information

Product Name	Potassium 2-Thiophenoyltrifluoroborate
CAS No.	1622923-63-0
Molecular Formula	C5H3BF3KOS
Molecular Weight	217.95 g/mol
Synonyms	Potassium (Thiophene-2-carbonyl)trifluoroborate; Potassium 2-Carboxythiophenetrifluoroborate; 2-Thiopheneboronic Acid, Potassium Trifluoroborate Salt; 2-Thienyltrifluoroborate Potassium Salt; Potassium 2-Thienyltrifluoroborate; Potassium 2-Thiopheneboronate Trifluoroborate; (Thiophen-2-yl)-trifluoroboronic Acid Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium 2-Thiophenoyltrifluoroborate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B, ¹⁹F), HPLC for purity assessment, and KF titration for moisture content, to ensure consistency and reliability for critical synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹¹B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Potassium Content	17.0% - 19.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.