Description

Sodium Tetrahydrofuran-3-Sulfinate is a specialized organosulfur compound that serves as a versatile nucleophilic sulfinate reagent. This chemical is of significant value in advanced organic synthesis, particularly for the introduction of sulfonyl groups under mild conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the sulfonylation of heterocycles and other sensitive scaffolds in active pharmaceutical ingredient (API) development.
• Cross-Coupling Reactions: Acts as a sulfinate source in transition-metal catalyzed cross-coupling for C-S bond formation.
• Polymer & Materials Chemistry: Used to incorporate sulfinate functionalities into monomers or polymers for specialty materials.
• Agrochemical Research: Employed in the synthesis of novel sulfone-containing compounds for crop protection agents.
• Ligand & Catalyst Development: Useful for preparing sulfonated ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Facilitates the bioconjugation and labeling of biomolecules via sulfonyl linkages.

Basic Information

Product Name	Sodium Tetrahydrofuran-3-Sulfinate
CAS No.	1622013-59-5
Molecular Formula	C4H7NaO3S
Molecular Weight	158.15 g/mol
Synonyms	Sodium 3-Sulfinatotetrahydrofuran; Tetrahydrofuran-3-sulfinic acid sodium salt; 3-Thiolan-1-oxide 1-sodium salt; Sodium 3,4-dihydro-2H-thiophene-1-oxide; Sodium THF-3-sulfinate; Sulfolene sodium salt derivative; 3-Sulfolene sodium sulfinate
EINECS	Contact for details

Quality Control

Our Sodium Tetrahydrofuran-3-Sulfinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including NMR, HPLC, and elemental analysis to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.