Description

Potassium (4-Chloro-2-Methylphenyl)Trifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its value lies in its exceptional stability and reactivity, serving as a superior alternative to traditional boronic acids in cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for complex molecule synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures, a common motif in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly in constructing substituted phenyl and heteroaryl scaffolds.
• Agrochemical Synthesis: Employed in creating advanced herbicides, fungicides, and insecticides that require specific chlorinated and methylated aromatic systems.
• Ligand and Catalyst Development: Serves as a precursor for developing new ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Utilized in the synthesis of organic electronic materials, such as those for OLEDs and conductive polymers, where precise molecular architecture is critical.
• Chemical Biology Probes: Acts as a handle for bioconjugation and the development of chemical probes for studying biological processes.

Basic Information

Product Name	Potassium (4-Chloro-2-Methylphenyl)Trifluoroborate
CAS No.	1620108-43-1
Molecular Formula	C7H6BClF3K
Molecular Weight	232.48 g/mol
Synonyms	Potassium (4-Chloro-o-tolyl)trifluoroborate; Potassium 4-Chloro-2-methylphenyltrifluoroborate; (4-Chloro-2-methylphenyl)trifluoroborate Potassium Salt; 4-Chloro-2-methylbenzenetrifluoroborate Potassium Salt; 4-Chloro-2-methylphenyltrifluoroboronic Acid Potassium Salt; 4-Chloro-2-methyl-Benzeneboronic Acid, Trifluoro-, Potassium Salt; Potassium Trifluoro(4-chloro-2-methylphenyl)borate
EINECS	Contact for details

Quality Control

Our Potassium (4-Chloro-2-Methylphenyl)Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B, ¹⁹F), HPLC for purity, and KF titration for moisture content, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹¹B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Potassium Content	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.