Description

7H-Imidazo[4,5-C]Pyridazine, 4-(3-Bromo-4-Fluorophenyl)-7-Ethyl- is a high-value, heterocyclic organic compound featuring a fused imidazo-pyridazine core substituted with bromo-fluorophenyl and ethyl groups. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API intermediate) for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel drug candidates, particularly in oncology and targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Kinase Inhibitor Development: The imidazo[4,5-c]pyridazine scaffold is prevalent in the design of potent and selective kinase inhibitors for cancer treatment.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	7H-Imidazo[4,5-C]Pyridazine, 4-(3-Bromo-4-Fluorophenyl)-7-Ethyl-
CAS No.	1614246-28-4
Molecular Formula	C₁₃H₁₀BrFN₄
Molecular Weight	321.15 g/mol
Synonyms	4-(3-Bromo-4-fluorophenyl)-7-ethyl-7H-imidazo[4,5-c]pyridazine; 7-Ethyl-4-(3-bromo-4-fluorophenyl)-7H-imidazo[4,5-c]pyridazine; 4-(3-Bromo-4-fluorophenyl)-7-ethylimidazo[4,5-c]pyridazine; 1614246-28-4; 7H-Imidazo[4,5-c]pyridazine, 4-(3-bromo-4-fluorophenyl)-7-ethyl-; 4-(3-Bromo-4-fluorophenyl)-7-ethyl-7H-imidazo[4,5-c]pyridazine; 7-Ethyl-4-(3-bromo-4-fluorophenyl)imidazo[4,5-c]pyridazine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and LC-MS to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting critical specifications. Our quality commitment supports its use in cGMP-compliant pharmaceutical development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.