Description

2H-Pyran-4-Carboxamide, 4-Amino-n-[(1S,2E)-4-(2,3-Dihydro-1H-Indol-1-Yl)-1-Ethyl-4-Oxo-2-Buten-1-Yl]Tetrahydro- is a sophisticated chiral organic compound featuring a complex molecular architecture that integrates pyran, indoline, and amide functionalities. This compound is of significant interest as a key synthetic intermediate or a potential pharmacophore in advanced research and development. It is primarily sought after by pharmaceutical R&D organizations and specialty chemical manufacturers engaged in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Chemical Biology Probes: Employed in the development of molecular probes to study specific biological pathways and enzyme functions.
• Process Chemistry Development: Utilized in route scouting and optimization for the scalable production of complex target molecules.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	2H-Pyran-4-Carboxamide, 4-Amino-n-[(1S,2E)-4-(2,3-Dihydro-1H-Indol-1-Yl)-1-Ethyl-4-Oxo-2-Buten-1-Yl]Tetrahydro-
CAS No.	1613458-70-0
Molecular Formula	C20H25N3O3
Molecular Weight	355.43 g/mol
Synonyms	4-Amino-N-[(1S,2E)-4-(2,3-dihydro-1H-indol-1-yl)-1-ethyl-4-oxo-2-buten-1-yl]tetrahydro-2H-pyran-4-carboxamide; (1S,2E)-1-Ethyl-4-(2,3-dihydro-1H-indol-1-yl)-4-oxo-2-buten-1-amine derivative; Tetrahydro-2H-pyran-4-carboxamide, 4-amino-N-[(1S,2E)-4-(2,3-dihydro-1H-indol-1-yl)-1-ethyl-4-oxobut-2-en-1-yl]-; 1613458-70-0; Chiral Pyran-Indoline Amide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and purity. All materials are characterized using advanced analytical techniques including HPLC, NMR, and LC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.