Description

Potassium 3,6-Dihydro-2H-Pyran-4-Trifluoroborate is a high-value organotrifluoroborate salt, a crucial class of reagents in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity, serving as a versatile building block for the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for carbon-carbon bond formation. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for complex molecule synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Development: Used in the research and production of novel herbicides, fungicides, and insecticides that require the incorporation of functionalized pyran or dihydropyran motifs.
• Material Science & Functional Polymers: Enables the synthesis of specialized monomers and polymers with tailored electronic or physical properties for advanced material applications.
• Chemical Biology & Probe Development: Employed in the creation of bioconjugates and molecular probes for diagnostic and research purposes due to its robust chemical handle.
• Catalyst & Ligand Preparation: Serves as a precursor for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Academic & Industrial R&D: A fundamental reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories worldwide.

Basic Information

Product Name	Potassium 3,6-Dihydro-2H-Pyran-4-Trifluoroborate
CAS No.	1612893-03-4
Molecular Formula	C5H7BF3KO2
Molecular Weight	218.02 g/mol
Synonyms	Potassium (3,6-Dihydro-2H-pyran-4-yl)trifluoroborate; 4-(Trifluoroborato)-3,6-dihydro-2H-pyran Potassium Salt; 3,6-Dihydro-2H-pyran-4-yltrifluoroboronic Acid Potassium Salt; Potassium 3,6-Dihydro-2H-pyran-4-yltrifluoroborate; 2H-Pyran, 3,6-dihydro-4-(trifluoroborato)-, potassium salt (1:1); Potassium 4-Trifluoroborato-3,6-dihydro-2H-pyran; DHP-BF3K; 4-Potassium Trifluoroborate-3,6-dihydro-2H-pyran
EINECS	Contact for details

Quality Control

Our production of Potassium 3,6-Dihydro-2H-Pyran-4-Trifluoroborate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including NMR (1H, 11B, 19F), HPLC, and elemental analysis, to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
1H NMR Purity	≥ 97%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.