Description

(2S,3S,4R,5S,6R)-2-(3-(4-Chlorobenzyl)-4-Methylphenyl)-6-(Methylthio)Tetrahydro-2H-Pyran-3,4,5-Triyl Triacetate is a high-purity, advanced pharmaceutical intermediate with a complex stereochemistry that is critical for its biological activity. This compound matters because it serves as a key building block in the synthesis of novel therapeutic agents, particularly in the development of enzyme inhibitors and other targeted small-molecule drugs. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex, biologically active molecules for drug discovery programs.
• Enzyme Inhibitor Research: Used as a core scaffold or derivatization point in the development of potent and selective enzyme inhibitors for various disease targets.
• Medicinal Chemistry: Serves as a versatile building block for structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for pre-clinical and clinical trial material production.
• Academic Research: Utilized in university and institutional labs for studying glycosidase mechanisms or developing new synthetic methodologies for complex carbohydrate analogs.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for the production of client-specific novel compounds under cGMP conditions.

Basic Information

Product Name	(2S,3S,4R,5S,6R)-2-(3-(4-Chlorobenzyl)-4-Methylphenyl)-6-(Methylthio)Tetrahydro-2H-Pyran-3,4,5-Triyl Triacetate
CAS No.	1610954-90-9
Molecular Formula	C30H33ClO7S
Molecular Weight	573.10 g/mol
Synonyms	1,2,3,4-Tetra-O-acetyl-6-S-methyl-6-thio-β-D-glucopyranose derivative; 6-Thio-β-D-glucopyranose tetraacetate derivative; 4-Chlorobenzyl phenyl methylthio tetraacetyl glucoside; (2S,3S,4R,5S,6R)-2-[3-[(4-Chlorophenyl)methyl]-4-methylphenyl]-6-methylsulfanyl-tetrahydropyran-3,4,5-triyl triacetate; 6-S-Methyl-6-thio-β-D-glucopyranose 1,2,3,4-tetraacetate aryl derivative; CAS 1610954-90-9
EINECS	Contact for details

Quality Control

Our (2S,3S,4R,5S,6R)-2-(3-(4-Chlorobenzyl)-4-Methylphenyl)-6-(Methylthio)Tetrahydro-2H-Pyran-3,4,5-Triyl Triacetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chiral HPLC to confirm stereochemical purity and identity. Certificates of Analysis (COA) detailing purity, impurity profile, and other critical parameters are provided with every shipment. We support development and cGMP-grade requirements, with specifications tailored to your project phase.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.