Description

Benzofuro[2,3-B]Pyridin-8-Yl Trifluoromethanesulfonate is a high-value triflate ester building block used in advanced organic synthesis. This compound is critical for facilitating challenging cross-coupling reactions and constructing complex heterocyclic scaffolds. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and fungicides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced organic electronic materials and polymers.
• Catalytic Cross-Coupling Reactions: An excellent electrophile in palladium-catalyzed reactions such as Suzuki, Negishi, and Stille couplings to form new carbon-carbon bonds.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to tag or modify biomolecules for studying biological pathways and protein function.

Basic Information

Product Name	Benzofuro[2,3-B]Pyridin-8-Yl Trifluoromethanesulfonate
CAS No.	1609373-92-3
Molecular Formula	C13H8F3NO4S
Molecular Weight	331.27 g/mol
Synonyms	8-(Trifluoromethanesulfonyloxy)benzofuro[2,3-b]pyridine; Benzofuro[2,3-b]pyridin-8-yl triflate; 8-Triflyloxybenzofuro[2,3-b]pyridine; 8-(Trifluoromethylsulfonyloxy)benzofuro[2,3-b]pyridine; Benzofuro[2,3-b]pyridin-8-ol triflate; Trifluoromethanesulfonic acid benzofuro[2,3-b]pyridin-8-yl ester
EINECS	Contact for details

Quality Control

Our Benzofuro[2,3-B]Pyridin-8-Yl Trifluoromethanesulfonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.