Description

trans-2-(4-(Methoxycarbonyl)Phenyl)Cyclopropanecarboxylic Acid CAS NO 1597427-16-1 is a high-purity, synthetically valuable cyclopropane derivative. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate for the development of novel active ingredients. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate the rigid, stereochemically defined cyclopropane scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, metabolic diseases, and anti-inflammatory agents.
• Agrochemical Research: Used as a precursor for developing novel pesticides and herbicides, where the cyclopropane ring can enhance biological activity and stability.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialized polymers and advanced organic materials.
• Academic & Contract Research: Essential for chemical biology studies and process chemistry research in academic institutions and CROs (Contract Research Organizations).
• Custom Synthesis Building Block: Supplied for bespoke synthesis projects requiring a specific, high-quality cyclopropane carboxylic acid derivative.

Basic Information

Product Name	trans-2-(4-(Methoxycarbonyl)Phenyl)Cyclopropanecarboxylic Acid
CAS No.	1597427-16-1
Molecular Formula	C12H12O4
Molecular Weight	220.22 g/mol
Synonyms	(1R,2S)-rel-2-[4-(Methoxycarbonyl)phenyl]cyclopropanecarboxylic Acid; Methyl 4-[(1R,2S)-2-(Carboxy)cyclopropyl]benzoate; trans-4-(Methoxycarbonyl)phenylcyclopropanecarboxylic Acid; (1R,2S)-2-(4-Methoxycarbonylphenyl)cyclopropane-1-carboxylic Acid; Cyclopropanecarboxylic acid, 2-[4-(methoxycarbonyl)phenyl]-, trans-; Benzoic acid, 4-[(1R,2S)-2-carboxycyclopropyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our trans-2-(4-(Methoxycarbonyl)Phenyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and cGMP standards for advanced intermediates. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.