Description

3-Chloro-4-(Hydroxymethyl)-Benzoic Acid is a versatile aromatic carboxylic acid derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its bifunctional structure, featuring both a carboxylic acid and a hydroxymethyl group on a chlorinated benzene ring, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where its chlorinated benzoic acid core provides a bioactive scaffold.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or a modifying agent in the production of specialty polymers and liquid crystal materials for electronic displays.
• Organic Synthesis Building Block: Employed in coupling reactions (e.g., esterification, amidation) and as a starting material for synthesizing more complex heterocyclic compounds in fine chemical production.
• Chemical Research & Development: A standard reagent in academic and industrial labs for methodological studies in synthetic organic chemistry and catalysis.

Basic Information

Product Name	3-Chloro-4-(Hydroxymethyl)-Benzoic Acid
CAS No.	1594779-14-2
Molecular Formula	C8H7ClO3
Molecular Weight	186.59 g/mol
Synonyms	3-Chloro-4-(hydroxymethyl)benzoic acid; 4-(Hydroxymethyl)-3-chlorobenzoic acid; Benzoic acid, 3-chloro-4-(hydroxymethyl)-; 3-Chloro-4-carboxymethylbenzoic acid (common misnomer); 3-Chloro-4-(hydroxymethyl)benzenecarboxylic acid; 3-Chloro-4-hydroxymethyl benzoate (acid form); 1594779-14-2; 3-Cl-4-HMBA
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-(Hydroxymethyl)-Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the exacting standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.