Description

3-(Bromomethyl)-2,4-Dichloro-1,5-Dimethoxybenzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the precise construction of complex molecular architectures through its reactive bromomethyl and chloro substituents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery and development pipelines.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with tailored properties.
• Cross-Coupling Reactions: An effective substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination to form new carbon-carbon or carbon-heteroatom bonds.
• Functional Group Transformation: The bromomethyl group allows for further functionalization to alcohols, amines, or ethers, expanding synthetic utility.
• Ligand and Catalyst Development: Used in the preparation of complex chelating ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	3-(Bromomethyl)-2,4-Dichloro-1,5-Dimethoxybenzene
CAS No.	1589080-79-4
Molecular Formula	C9H9BrCl2O2
Molecular Weight	308.98 g/mol
Synonyms	1-Bromomethyl-2,4-dichloro-3,6-dimethoxybenzene; 2,4-Dichloro-3,6-dimethoxybenzyl bromide; 2,4-Dichloro-1,5-dimethoxy-3-(bromomethyl)benzene; 3-(Bromomethyl)-2,4-dichloro-1,5-dimethoxybenzene; 1,5-Dimethoxy-2,4-dichloro-3-(bromomethyl)benzene; Benzene, 1-(bromomethyl)-2,4-dichloro-3,6-dimethoxy-; 2,4-Dichloro-3,6-dimethoxy-α-bromotoluene
EINECS	Contact for details

Quality Control

Our 3-(Bromomethyl)-2,4-Dichloro-1,5-Dimethoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.