Description

1-(2,4,6-Trimethylphenyl)-3-[(1R,2R,3R,5S)-(-)-Isopinocampheyl]Imidazolium Chloride is a high-value, chiral N-heterocyclic carbene (NHC) precursor salt, essential for asymmetric catalysis. Its core value lies in enabling highly enantioselective transformations, crucial for producing single-isomer intermediates in pharmaceutical and fine chemical synthesis. This compound is primarily needed by research institutions and industrial chemists developing novel catalytic processes for APIs, agrochemicals, and advanced materials.

Application

• As a chiral ligand precursor for asymmetric transition metal catalysis (e.g., Pd, Ru, Ir complexes).
• Enabling enantioselective C-C and C-X bond-forming reactions in pharmaceutical research and development.
• Use in the synthesis of high-value, single-enantiomer active pharmaceutical ingredients (APIs).
• Catalyst development for fine chemical and agrochemical manufacturing.
• Academic research in organometallic chemistry and asymmetric synthesis methodologies.
• Potential application in materials science for creating chiral polymeric or supramolecular structures.

Basic Information

Product Name	1-(2,4,6-Trimethylphenyl)-3-[(1R,2R,3R,5S)-(-)-Isopinocampheyl]Imidazolium Chloride
CAS No.	1583244-12-5
Molecular Formula	C22H31ClN2
Molecular Weight	358.95 g/mol
Synonyms	(-)-1-(2,4,6-Trimethylphenyl)-3-[(1R,2R,3R,5S)-(-)-Isopinocampheyl]imidazolium chloride; (1R,2R,3R,5S)-(-)-1-(2,4,6-Trimethylphenyl)-3-(isopinocampheyl)imidazolium chloride; Chiral Mesityl-Isopinocampheyl Imidazolium Chloride; Chiral NHC Salt Precursor; (1R,2R,3R,5S)-1-(2,4,6-Trimethylphenyl)-3-(7,7-dimethyl-2-bicyclo[3.1.1]heptanyl)imidazol-1-ium chloride
EINECS	Contact for details

Quality Control

Our 1-(2,4,6-Trimethylphenyl)-3-[(1R,2R,3R,5S)-(-)-Isopinocampheyl]Imidazolium Chloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high chiral purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles. We adhere to cGMP principles where applicable to support our customers' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.