Description

(1S,2R,3S,4R)-3-(((tert-Butyldimethylsilyl)Oxy)Methyl)-2-(5-Oxopentyl)-4-((Tetrahydro-2H-Pyran-2-Yl)Oxy)Cyclopentyl Acetate CAS NO 1574525-26-0 is a high-purity, advanced pharmaceutical intermediate characterized by its complex, stereochemically defined cyclopentane core. This compound is a critical building block in the synthesis of complex bioactive molecules, particularly in the development of prostaglandin analogs and other specialized therapeutics. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates requiring precise stereochemical control.

Application

• Key Intermediate in Prostaglandin Synthesis: Serves as a crucial chiral precursor for the production of prostaglandin and prostacyclin analogs used in ophthalmology and cardiovascular medicine.
• Pharmaceutical Research & Development (R&D): Employed in medicinal chemistry for the construction of complex, stereospecific molecular architectures in drug discovery programs.
• Synthesis of Specialized Bioactive Compounds: Used in the preparation of other high-value intermediates targeting specific biological pathways.
• Process Chemistry & Scale-Up: Provides a reliable, high-quality starting material for process optimization and pilot-scale manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(1S,2R,3S,4R)-3-(((tert-Butyldimethylsilyl)Oxy)Methyl)-2-(5-Oxopentyl)-4-((Tetrahydro-2H-Pyran-2-Yl)Oxy)Cyclopentyl Acetate
CAS No.	1574525-26-0
Molecular Formula	C24H44O6Si
Molecular Weight	456.70 g/mol
Synonyms	(1S,2R,3S,4R)-3-(((tert-Butyldimethylsilyl)oxy)methyl)-2-(5-oxopentyl)-4-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl acetate; Cyclopentyl acetate, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl-2-(5-oxopentyl)-4-(tetrahydro-2H-pyran-2-yl)oxy-, (1S,2R,3S,4R)-; TBDMS- and THP-Protected Prostaglandin Intermediate; (1S,2R,3S,4R)-3-((tert-Butyldimethylsilyloxy)methyl)-2-(5-oxopentyl)-4-(tetrahydropyran-2-yloxy)cyclopentyl acetate
EINECS	Contact for details

Quality Control

Our (1S,2R,3S,4R)-3-(((tert-Butyldimethylsilyl)Oxy)Methyl)-2-(5-Oxopentyl)-4-((Tetrahydro-2H-Pyran-2-Yl)Oxy)Cyclopentyl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high stereochemical purity and chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.