Description

5-Methyl-2-(Tributylstannyl)-1,3-Oxazole is a specialized organotin reagent featuring a functionalized oxazole heterocycle. This compound is a critical building block in advanced organic synthesis, particularly for Stille cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of complex drug candidates, especially those containing heterocyclic cores, via palladium-catalyzed Stille coupling.
• Agrochemical Research: Used to construct novel active ingredients for crop protection agents, leveraging the oxazole moiety's bioactivity.
• Materials Science: Serves as a precursor for creating functional organic materials, such as organic semiconductors or liquid crystals, through controlled cross-coupling.
• Chemical Synthesis: An essential tool in academic and industrial R&D for constructing C-C bonds under mild conditions, offering excellent functional group tolerance.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts where the oxazole-tin bond is strategically incorporated.

Basic Information

Product Name	5-Methyl-2-(Tributylstannyl)-1,3-Oxazole
CAS No.	1571145-57-7
Molecular Formula	C16H31NOSn
Molecular Weight	388.13 g/mol
Synonyms	2-(Tributylstannyl)-5-methyl-1,3-oxazole; 5-Methyl-2-(tributylstannyl)oxazole; Tributyl(5-methyl-2-oxazolyl)stannane; 1,3-Oxazole, 5-methyl-2-(tributylstannyl)-; Stannane, tributyl(5-methyl-2-oxazolyl)-; 5-Methyl-2-oxazole tributylstannane; Organotin oxazole reagent
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-(Tributylstannyl)-1,3-Oxazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed via NMR (1H, 13C), HPLC, and elemental analysis to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin (Sn) Content	30.0 - 31.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.