Description

7-((1R,2S)-2-Aminocyclohexylamino)-5-(3-Methyl-1H-Indol-7-Ylamino)-3H-Pyrido[3,4-D]Pyridazin-4-One is a high-purity, advanced pharmaceutical intermediate designed for research and development in targeted drug discovery. This compound is valued for its specific stereochemistry and functional groups, which are critical for modulating biological activity in therapeutic candidates. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Preclinical Drug Development: Serves as a critical material for producing compounds for in vitro and in vivo biological testing.
• Process Chemistry: Employed in route scouting and scale-up optimization for potential Active Pharmaceutical Ingredient (API) manufacturing.
• Biochemical Tool Compound: May be used to develop probes for studying specific enzymatic pathways in academic and industrial research settings.

Basic Information

Product Name	7-((1R,2S)-2-Aminocyclohexylamino)-5-(3-Methyl-1H-Indol-7-Ylamino)-3H-Pyrido[3,4-D]Pyridazin-4-One
CAS No.	1564272-40-7
Molecular Formula	C22H26N8O
Molecular Weight	418.50 g/mol
Synonyms	7-[(1R,2S)-2-Aminocyclohexylamino]-5-[(3-methyl-1H-indol-7-yl)amino]-3H-pyrido[3,4-d]pyridazin-4-one; 7-((1R,2S)-2-Aminocyclohexylamino)-5-(3-methyl-1H-indol-7-ylamino)-3H-pyrido[3,4-d]pyridazin-4-one; 1564272-40-7; UNII-7S0K3J5Q2K; 7S0K3J5Q2K; (1R,2S)-N2-[5-[(3-methyl-1H-indol-7-yl)amino]-4-oxo-3H-pyrido[3,4-d]pyridazin-7-yl]cyclohexane-1,2-diamine
EINECS	Contact for details

Quality Control

Our 7-((1R,2S)-2-Aminocyclohexylamino)-5-(3-Methyl-1H-Indol-7-Ylamino)-3H-Pyrido[3,4-D]Pyridazin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and oxidation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.