Description

3-Chloro-2,5-Difluorobenzyl Amine is a versatile and high-value fluorinated benzylamine building block, essential for advanced organic synthesis. Its unique halogenated structure makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro and chloro substituents enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Useful as a reactive handle for bioconjugation and the development of chemical probes and affinity tags.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Chloro-2,5-Difluorobenzyl Amine
CAS No.	1557849-73-6
Molecular Formula	C7H6ClF2N
Molecular Weight	177.58 g/mol
Synonyms	(3-Chloro-2,5-difluorophenyl)methanamine; 1-(3-Chloro-2,5-difluorophenyl)methanamine; 3-Chloro-2,5-difluorobenzylamine; Benzenemethanamine, 3-chloro-2,5-difluoro-; 2,5-Difluoro-3-chlorobenzylamine; (3-Chloro-2,5-difluorobenzyl)amine; 1557849-73-6; 3-Chloro-2,5-difluoro-benzenemethanamine
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,5-Difluorobenzyl Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for demanding research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.