Description

3,6-Dichloro-4-(2,2,2-trifluoroethoxy)pyridazine is a high-purity fluorinated pyridazine derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines halogen and fluoroalkoxy substituents to enable precise structural modifications in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning the physicochemical properties of complex molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Serves as a critical precursor in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridazine core.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and electronic materials where the introduction of fluorine atoms enhances thermal stability and electronic properties.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing chemical probes, enzyme inhibitors, and molecular tags in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale API (Active Pharmaceutical Ingredient) development.

Basic Information

Product Name	3,6-Dichloro-4-(2,2,2-trifluoroethoxy)pyridazine
CAS No.	1557411-83-2
Molecular Formula	C6H3Cl2F3N2O
Molecular Weight	247.00 g/mol
Synonyms	4-(2,2,2-Trifluoroethoxy)-3,6-dichloropyridazine; 3,6-Dichloro-4-(2,2,2-trifluoroethoxy)-1,2-diazine; 3,6-Dichloro-4-(β,β,β-trifluoroethoxy)pyridazine; Pyridazine, 3,6-dichloro-4-(2,2,2-trifluoroethoxy)-; 1557411-83-2
EINECS	Contact for details

Quality Control

Every batch of 3,6-Dichloro-4-(2,2,2-trifluoroethoxy)pyridazine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for advanced R&D and scale-up processes. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by validated methods including HPLC, GC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.