Description

Methanesulfonylmethyl-Carbamic Acid tert-Butyl Ester is a high-purity, protected carbamate derivative widely used as a key synthetic intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing sulfonamide or protected amine functionalities.
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and peptidomimetics where the tert-butyloxycarbonyl (Boc) and methanesulfonylmethyl groups serve as protective or directing groups.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides that require specific carbamate or sulfone motifs.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and enzyme inhibitors for target validation and mechanistic studies.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Used in research laboratories for methodological development and exploring new chemical reactions involving protected amines.

Basic Information

Product Name	Methanesulfonylmethyl-Carbamic Acid tert-Butyl Ester
CAS No.	1555965-44-0
Molecular Formula	C8H17NO4S
Molecular Weight	223.29 g/mol
Synonyms	tert-Butyl N-[(methylsulfonyl)methyl]carbamate; Boc-NH-CH2-SO2-CH3; (Methanesulfonylmethyl)carbamic acid tert-butyl ester; N-[(Methylsulfonyl)methyl]carbamic Acid 1,1-Dimethylethyl Ester; N-Boc-aminomethanesulfonylmethane; 1,1-Dimethylethyl N-[(methylsulfonyl)methyl]carbamate; tert-Butyl ((methylsulfonyl)methyl)carbamate
EINECS	Contact for details

Quality Control

Our Methanesulfonylmethyl-Carbamic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We adhere to industry-standard analytical methods including HPLC, NMR, and IR spectroscopy for identity confirmation and purity assessment. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and stored under anhydrous conditions or with appropriate desiccants to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.