Description

4-(Hydroxymethyl)Norbornane-1-Carboxylic Acid is a high-purity, functionalized norbornane derivative of significant interest in advanced organic synthesis. This compound matters as a versatile chiral building block, offering a rigid bicyclic scaffold with both carboxylic acid and hydroxymethyl functional groups for precise molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and specialty chemical industries for applications such as chiral ligand synthesis, polymer modification, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Chiral Ligand & Catalyst Synthesis: Utilized as a precursor for synthesizing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with unique thermal and mechanical properties, such as polyimides or epoxy resins.
• Agrochemical Research: Employed in the design and synthesis of new generation herbicides and pesticides with enhanced efficacy and selectivity.
• Material Science: Used in the development of liquid crystals, organic semiconductors, and other functional materials due to its rigid, shape-persistent core.
• Chemical Biology & Proteomics: Functions as a scaffold or linker in the synthesis of molecular probes and bioconjugates for studying biological systems.

Basic Information

Product Name	4-(Hydroxymethyl)Norbornane-1-Carboxylic Acid
CAS No.	1551365-19-5
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	4-(Hydroxymethyl)bicyclo[2.2.1]heptane-1-carboxylic acid; 4-(Hydroxymethyl)-1-norbornanecarboxylic acid; 1-Norbornanecarboxylic acid, 4-(hydroxymethyl)-; Bicyclo[2.2.1]heptane-1-carboxylic acid, 4-(hydroxymethyl)-; 4-Carboxynorbornane-1-methanol; Hydroxymethyl norbornane carboxylic acid; Norbornane hydroxymethyl carboxylic acid; 4-HM-NCA
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)Norbornane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.