Description

4-Ethynylcyclohexan-1-One is a high-value, specialized organic building block featuring both a ketone and an alkyne functional group within a cyclohexane ring. This unique bifunctional structure makes it a versatile intermediate for synthesizing complex molecules in advanced research and development. It is particularly valuable for pharmaceutical chemists and agrochemical researchers developing novel active ingredients, as well as for materials scientists working on specialty polymers and advanced organic frameworks.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that require specific, rigid molecular architectures.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, dendrimers, and metal-organic frameworks (MOFs) with tailored properties.
• Organic Synthesis Building Block: Enables click chemistry reactions via its alkyne group and further functionalization via its ketone group, facilitating rapid library synthesis for high-throughput screening.
• Ligand and Catalyst Development: Used to create novel chiral ligands and organometallic catalysts for asymmetric synthesis applications.
• Fine Chemical Production: Employed in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	4-Ethynylcyclohexan-1-One
CAS No.	1549050-50-1
Molecular Formula	C8H10O
Molecular Weight	122.16 g/mol
Synonyms	4-Ethynylcyclohexanone; 4-Ethynyl-1-cyclohexanone; 1-Cyclohexanone, 4-ethynyl-; 4-Ethynylcyclohexan-1-one; 4-Ethynyl-cyclohexanone; Cyclohexanone, 4-ethynyl-
EINECS	Contact for details

Quality Control

Our 4-Ethynylcyclohexan-1-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and adherence to ISO 9001 standards underpin our reliable supply chain for research and development-scale quantities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in opaque secondary packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.