Description

(R)-2-Methyl-N-(3-(Trifluoromethyl)Benzylidene)Propane-2-Sulfinamide is a high-purity chiral sulfinamide building block, essential for the stereoselective synthesis of complex organic molecules. Its value lies in its role as a versatile chiral auxiliary and ligand, enabling the production of enantiomerically pure intermediates critical for advanced research and development. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• As a chiral auxiliary in asymmetric synthesis for the construction of stereogenic centers.
• Key intermediate in the research and development of pharmaceutical candidates, particularly for CNS and oncology targets.
• Precursor for the synthesis of chiral ligands and catalysts used in metal-mediated transformations.
• Building block for agrochemical active ingredients requiring specific stereochemistry for efficacy.
• Used in academic and industrial research for methodology development in organic chemistry.
• Component in the synthesis of specialty fine chemicals and advanced materials.

Basic Information

Product Name	(R)-2-Methyl-N-(3-(Trifluoromethyl)Benzylidene)Propane-2-Sulfinamide
CAS No.	1547490-91-4
Molecular Formula	C13H16F3NOS
Molecular Weight	291.33 g/mol
Synonyms	(R)-2-Methyl-N-[(3-(trifluoromethyl)phenyl)methylene]propane-2-sulfinamide; (R)-N-((3-(Trifluoromethyl)benzylidene)-2-methylpropane-2-sulfinamide; (R)-2-Methyl-2-propanesulfinamide, N-[(3-(trifluoromethyl)phenyl)methylene]-; (R)-tert-Butanesulfinamide, N-[(3-(trifluoromethyl)phenyl)methylene]-; (R)-N-(3-(Trifluoromethyl)benzylidene)-tert-butanesulfinamide; (R)-N-(α,α,α-Trifluoro-m-tolylidene)-2-methyl-2-propanesulfinamide; (R)-Sulfinamide Chiral Auxiliary CAS 1547490-91-4
EINECS	Contact for details

Quality Control

Our (R)-2-Methyl-N-(3-(Trifluoromethyl)Benzylidene)Propane-2-Sulfinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.