Description

1-(Piperidin-4-yl)azetidin-3-ol dihydrochloride is a high-purity pharmaceutical intermediate and building block of significant importance in modern drug discovery. Its value lies in its unique bicyclic amine structure, which is a privileged scaffold for modulating biological activity, particularly in central nervous system (CNS) and other therapeutic targets. This compound is essential for research chemists and process development scientists in the pharmaceutical and biotechnology industries working on novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• CNS Drug Research: Used in the development of compounds targeting neurological disorders, leveraging its piperidine-azetidine scaffold.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular tools to study biological pathways and protein function.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of target molecules.
• Library Synthesis for High-Throughput Screening: Used to generate diverse compound libraries to identify new lead structures.
• Academic & Institutional Research: A valuable reagent for universities and research institutes conducting fundamental and applied chemical research.

Basic Information

Product Name	1-(Piperidin-4-yl)azetidin-3-ol dihydrochloride
CAS No.	1537465-19-2
Molecular Formula	C8H18Cl2N2O
Molecular Weight	229.15 g/mol
Synonyms	3-Azetidinol, 1-(4-piperidinyl)-, dihydrochloride; 1-(Piperidin-4-yl)azetidin-3-ol hydrochloride (1:2); 1-(4-Piperidyl)azetidin-3-ol dihydrochloride; 3-Hydroxy-1-(4-piperidyl)azetidine dihydrochloride; Azetidin-3-ol, 1-(4-piperidinyl)-, dihydrochloride; 1537465-19-2; 1-Piperidin-4-yl-azetidin-3-ol dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Piperidin-4-yl)azetidin-3-ol dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available for every lot upon request, providing full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.