Description

n-Benzyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, catalyst development, and functional polymer synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing biphenyl or heterocyclic motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized to synthesize tagged molecules for studying biological pathways and protein interactions.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic routes in organic chemistry laboratories.

Basic Information

Product Name	n-Benzyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	1535182-67-2
Molecular Formula	C19H24BNO2
Molecular Weight	309.21 g/mol
Synonyms	2-((Benzylamino)methyl)phenylboronic acid pinacol ester; N-Benzyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine; (2-((Benzylamino)methyl)phenyl)boronic acid pinacol ester; 2-(Benzylaminomethyl)phenylboronic acid pinacol ester; Benzenamine, N-benzyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; B-(2-((Benzylamino)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Every batch of n-Benzyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for sensitive cross-coupling applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.