Description

2-(Cyanomethyl)-5,7-Difluorobenzimidazole is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzimidazole core functionalized with a cyanomethyl group and fluorine atoms. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this specialized intermediate to develop next-generation therapeutic agents with enhanced potency and selectivity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzimidazole-based drug candidates targeting various disease pathways.
• Oncology Research: Used in the development of small molecule inhibitors and targeted cancer therapies due to the benzimidazole scaffold's affinity for biological targets.
• Antiviral Agent Synthesis: Serves as a core structure for creating compounds with potential activity against viral proteases and polymerases.
• Agrochemical Development: Employed in research for creating new fungicides and herbicides, leveraging the biological activity of the difluorobenzimidazole moiety.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique optical or electronic properties.
• Chemical Biology: Utilized as a molecular probe or tag in biochemical assays and diagnostic development.

Basic Information

Item	Details
Product Name	2-(Cyanomethyl)-5,7-Difluorobenzimidazole
CAS No.	1533815-59-6
Molecular Formula	C9H5F2N3
Molecular Weight	193.16 g/mol
Synonyms	5,7-Difluoro-2-(cyanomethyl)-1H-benzimidazole; 1H-Benzimidazole, 2-(cyanomethyl)-5,7-difluoro-; 2-Cyanomethyl-5,7-difluorobenzimidazole; 5,7-Difluoro-1H-benzimidazole-2-acetonitrile; 2-(Cyanomethyl)-5,7-difluoro-1H-benzo[d]imidazole
EINECS	Contact for details

Quality Control

Our 2-(Cyanomethyl)-5,7-Difluorobenzimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.