Description

1-(2,2-Difluoroethyl)Cyclobutane-1-Carboxylic Acid is a high-value, fluorinated cyclobutane carboxylic acid derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring a cyclobutane ring and a difluoroethyl side chain, makes it an essential intermediate for introducing conformational rigidity and fluorine atoms into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Potential monomer or additive for developing specialty polymers with unique thermal or surface properties.
• Fluorine Chemistry Building Block: A versatile starting material for further functionalization in the synthesis of complex fluorinated compounds.

Basic Information

Product Name	1-(2,2-Difluoroethyl)Cyclobutane-1-Carboxylic Acid
CAS No.	1529329-33-6
Molecular Formula	C7H10F2O2
Molecular Weight	164.15 g/mol
Synonyms	1-(2,2-Difluoroethyl)cyclobutane-1-carboxylic acid; Cyclobutane-1-carboxylic acid, 1-(2,2-difluoroethyl)-; 1-(2,2-Difluoroethyl)-1-cyclobutanecarboxylic Acid; 1-(2,2-Difluoroethyl)cyclobutane carboxylic acid; Difluoroethyl Cyclobutanecarboxylate; 1529329-33-6; 1-(2,2-Difluoroethyl)cyclobutylcarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(2,2-Difluoroethyl)Cyclobutane-1-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO 9001 standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. Due to its acidic nature, handle with appropriate engineering controls and personal protective equipment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.