Description

(1-Cyanocyclobutyl)Methyl 4-Methylbenzene-1-Sulfonate is a specialized organic sulfonate ester building block of significant interest in advanced synthetic chemistry. Its molecular architecture, featuring both a cyano-substituted cyclobutyl ring and a tosylate leaving group, makes it a versatile intermediate for constructing complex, strained-ring systems. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries. It serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those containing strained carbocyclic or heterocyclic frameworks.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the cyclobutane moiety can impart unique biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent precursor in the development of advanced polymers with specific thermal or mechanical properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for cycloaddition reactions, nucleophilic substitution, and as a scaffold for further functionalization.
• Ligand and Catalyst Development: Useful precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	(1-Cyanocyclobutyl)Methyl 4-Methylbenzene-1-Sulfonate
CAS No.	1523618-15-6
Molecular Formula	C13H15NO3S
Molecular Weight	265.33 g/mol
Synonyms	(1-Cyanocyclobutyl)methyl tosylate; 4-Methylbenzenesulfonic acid (1-cyanocyclobutyl)methyl ester; p-Toluenesulfonic acid (1-cyanocyclobutyl)methyl ester; (1-Cyanocyclobutyl)methyl p-toluenesulfonate; Tosylate of (1-cyanocyclobutyl)methanol; Cyclobutane-1-carbonitrile, 1-[(4-methylphenyl)sulfonyloxy]methyl-; 1-[(Tosyloxy)methyl]cyclobutanecarbonitrile
EINECS	Contact for details

Quality Control

Our (1-Cyanocyclobutyl)Methyl 4-Methylbenzene-1-Sulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, purity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.