Description

3-(Hydroxymethyl)-3-Methylcyclobutan-1-One is a versatile and synthetically valuable cyclobutanone derivative, serving as a key chiral building block in advanced organic synthesis. Its unique strained ring structure functionalized with a hydroxymethyl group makes it a critical precursor for constructing complex molecular architectures with high stereochemical control. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries seeking to develop novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in developing central nervous system (CNS) agents and anti-infectives.
• Agrochemical Synthesis: Used in constructing bioactive molecules for crop protection, including herbicides and fungicides with novel modes of action.
• Ligand and Catalyst Development: Serves as a backbone for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers with tailored thermal and mechanical properties.
• Fragrance & Flavor Chemistry: Employed in the synthesis of complex odorants and flavor molecules that leverage its constrained cyclobutane ring.
• Academic & R&D: A valuable reagent for methodological studies in ring expansion, strain-release chemistry, and stereoselective transformations.

Basic Information

Product Name	3-(Hydroxymethyl)-3-Methylcyclobutan-1-One
CAS No.	1523617-87-9
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	3-Methyl-3-(hydroxymethyl)cyclobutanone; 3-Hydroxymethyl-3-methylcyclobutanone; 3-Methyl-3-(hydroxymethyl)cyclobutan-1-one; (3-Methyl-3-oxocyclobutyl)methanol; 1-Oxaspiro[2.2]pentane-4-methanol, 2-methyl-; Cyclobutanone, 3-(hydroxymethyl)-3-methyl-
EINECS	Contact for details

Quality Control

Our 3-(Hydroxymethyl)-3-Methylcyclobutan-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting R&D and process chemistry standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.