Description

3-(n-Cbz-Aminomethyl)Tetrahydropyran CAS NO 1523571-12-1 is a protected amino alcohol derivative featuring a carboxybenzyl (Cbz) protecting group on the aminomethyl functionality. This compound is a critical chiral building block in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily utilized by research organizations, fine chemical manufacturers, and pharmaceutical companies engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of APIs targeting neurological and cardiovascular diseases.
• Peptidomimetics Research: Used in the design and construction of peptide-like molecules with enhanced metabolic stability.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in stereoselective chemical transformations.
• Medicinal Chemistry: A versatile scaffold for constructing compound libraries in high-throughput screening and drug discovery programs.
• Custom Synthesis: Employed in the contract manufacturing of specialized fine chemicals and advanced intermediates.

Basic Information

Product Name	3-(n-Cbz-Aminomethyl)Tetrahydropyran
CAS No.	1523571-12-1
Molecular Formula	C14H19NO3
Molecular Weight	249.31 g/mol
Synonyms	3-[(Benzyloxycarbonylamino)methyl]tetrahydro-2H-pyran; 3-(Cbz-Aminomethyl)tetrahydropyran; 3-(N-Carbobenzyloxyaminomethyl)tetrahydropyran; 3-[(Phenylmethoxycarbonylamino)methyl]oxane; 1523571-12-1; 3-(Cbz-NH-CH2)-Tetrahydropyran; Benzyl N-[(oxan-3-yl)methyl]carbamate
EINECS	Contact for details

Quality Control

Our 3-(n-Cbz-Aminomethyl)Tetrahydropyran is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.