Description

Cyclopropaneacetic Acid, α-Amino-1-Methyl-, (Alphas)-, Hcl is a high-purity, non-proteinogenic amino acid derivative featuring a cyclopropane ring structure. This compound is a critical chiral building block in modern pharmaceutical research and development, valued for its ability to introduce conformational rigidity and unique steric properties into target molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs) and complex bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide mimetics and small molecule drugs targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological activity of lead compounds.
• Peptidomimetic Design: Incorporated into peptide backbones to enhance metabolic stability, bioavailability, and receptor selectivity.
• Process Chemistry & Scale-up: Serves as a starting material or advanced intermediate in the development of scalable, GMP-compliant synthetic routes for API manufacturing.
• Bioconjugation & Probe Development: Utilized in the creation of chemical probes and bioconjugates for biochemical and diagnostic applications.

Basic Information

Product Name	Cyclopropaneacetic Acid, α-Amino-1-Methyl-, (Alphas)-, Hcl
CAS No.	1523541-83-4
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	(αS)-α-Amino-α-methylcyclopropaneacetic acid hydrochloride; (S)-2-Amino-2-methylcyclopropaneacetic acid hydrochloride; (S)-1-Aminocyclopropane-1-carboxylic acid, α-methyl-, hydrochloride; (S)-2-Methyl-2-(aminomethyl)cyclopropanecarboxylic acid hydrochloride; Cyclopropaneacetic acid, α-amino-α-methyl-, (αS)-, hydrochloride; (S)-Amino-methyl-methyl-cyclopropyl-acetic acid hydrochloride; (S)-2-Amino-2-methyl-1-cyclopropanecarboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our Cyclopropaneacetic Acid, α-Amino-1-Methyl-, (Alphas)-, Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical characterization, including chiral purity verification, to meet the exacting standards of pharmaceutical applications. A detailed Certificate of Analysis (COA) providing full specification data, including results from HPLC, NMR, and optical rotation tests, is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.