Description

1-(2-Hydroxyethyl)Cyclopropanecarboxylic Acid is a versatile bifunctional organic building block featuring both a carboxylic acid and a terminal hydroxyl group on a cyclopropane scaffold. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), especially those requiring a rigid cyclopropane moiety to modulate biological activity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the cyclopropane ring can enhance efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) in asymmetric catalysis and material science.
• Polymer Modification: The dual functionality allows for incorporation into polymer chains as a cross-linking agent or to introduce pendant hydroxyl groups for further functionalization.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for producing specialty chemicals, flavors, and fragrances.
• Bioconjugation and Probe Synthesis: Useful in medicinal chemistry for creating molecular probes or antibody-drug conjugates (ADCs) due to its derivatizable acid and alcohol groups.

Basic Information

Product Name	1-(2-Hydroxyethyl)Cyclopropanecarboxylic Acid
CAS No.	1520462-70-7
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	2-(Cyclopropanecarbonyloxy)ethan-1-ol; 2-Hydroxyethyl cyclopropanecarboxylate; Cyclopropanecarboxylic acid 2-hydroxyethyl ester; (2-Hydroxyethoxy)cyclopropanecarboxylic acid; 1-(2-Hydroxyethyl)cyclopropane-1-carboxylic acid; HECPCA; Hydroxyethyl cyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Hydroxyethyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.