Description

2-Chloro-6-(Difluoromethoxy)Benzyl Amine is a high-purity, functionalized benzylamine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its unique halogenated and ether-substituted benzyl structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its amine functionality and aromatic core.
• Custom Synthesis and Contract Manufacturing: An essential substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Chloro-6-(Difluoromethoxy)Benzyl Amine
CAS No.	1515925-06-0
Molecular Formula	C8H8ClF2NO
Molecular Weight	207.60 g/mol
Synonyms	1-(2-Chloro-6-(difluoromethoxy)phenyl)methanamine; (2-Chloro-6-(difluoromethoxy)phenyl)methanamine; 2-Chloro-6-(difluoromethoxy)benzenemethanamine; 2-Chloro-α-(difluoromethoxy)benzylamine; Benzylamine, 2-chloro-6-(difluoromethoxy)-; 1515925-06-0; 2-Chloro-6-difluoromethoxybenzylamine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-(Difluoromethoxy)Benzyl Amine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.