Description

5-Fluoro-2H-Chromene-3-Carbonitrile is a high-purity fluorinated chromene derivative, a key synthetic intermediate in modern organic chemistry. Its value lies in its unique molecular scaffold, which combines a chromene core with a nitrile and fluorine substituent, enabling the construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing potential drug candidates, especially in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated chromene structure.
• Organic Synthesis: Serves as a versatile precursor for synthesizing more complex fused heterocycles, such as pyranoquinolines and other polycyclic frameworks.
• Material Science: Investigated for use in the synthesis of organic electronic materials, dyes, and fluorescent markers due to its conjugated system.
• Chemical Biology: Employed as a probe or scaffold in the design of enzyme inhibitors and molecular tools for biological studies.

Basic Information

Product Name	5-Fluoro-2H-Chromene-3-Carbonitrile
CAS No.	1512308-03-0
Molecular Formula	C10H6FNO
Molecular Weight	175.16 g/mol
Synonyms	5-Fluoro-2H-1-benzopyran-3-carbonitrile; 5-Fluorochromene-3-carbonitrile; 3-Cyano-5-fluoro-2H-chromene; 5-Fluoro-3-cyano-2H-chromene; 5-Fluoro-2H-1-benzopyran-3-carbonitrile; 1512308-03-0; 5-Fluoro-2H-chromene-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2H-Chromene-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For custom synthesis or specific purity requirements, our technical team is available to discuss tailored QC protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.