Description

Methyl 4-Ethynyltetrahydro-2H-Pyran-4-Carboxylate is a high-value, multifunctional building block characterized by its unique combination of a tetrahydro-2H-pyran ring, an ethynyl group, and a methyl ester moiety. This compound is essential for advanced organic synthesis, offering versatile reactivity for constructing complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its scaffold for bioactivity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced organic frameworks.
• Chemical Biology Probe: The alkyne functionality allows for click chemistry applications, such as bioconjugation and labeling in proteomics research.
• Academic & Industrial R&D: A versatile reagent for methodology development and exploring new synthetic routes in organic chemistry laboratories.

Basic Information

Product Name	Methyl 4-Ethynyltetrahydro-2H-Pyran-4-Carboxylate
CAS No.	1509901-08-9
Molecular Formula	C9H12O3
Molecular Weight	168.19 g/mol
Synonyms	Methyl 4-ethynyloxane-4-carboxylate; 4-Ethynyltetrahydro-2H-pyran-4-carboxylic acid methyl ester; 4-Carbomethoxy-4-ethynyltetrahydropyran; Methyl 4-ethynyltetrahydropyran-4-carboxylate; 1509901-08-9; Methyl 4-ethynyl-4-tetrahydropyrancarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4-Ethynyltetrahydro-2H-Pyran-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality supports applications requiring high-purity intermediates for research and cGMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its properties as a strong acid/organic solvent and being easily oxidized, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.